Understanding life at a molecular level
He felt keenly conscious of how barren all intellectual speculation is
when separated from action and experiment.
Oscar Wilde The Picture of Dorian Gray
Welcome to the website of Edelmiro Moman. I am a chemist. I did a PhD on the synthesis of vitamin D analogues in the group of Prof. Antonio Mourinho at the University of Santiago de Compostela, Galiza. During that time, I also explored a novel free radical tandem process of my invention and had the opportunity to collaborate with Prof. Yagamare Fall at the University of Vigo, as well as to carry out a research stay in the group of the late Prof. Henry Rapoport at the University of California, Berkeley.
After a brief postdoctoral stay in the group of Prof. Chrys Chatgilialoglu at the CNR-Bologna, I moved to the Royal College of Surgeons in Ireland (RCSI) to collaborate with Prof. Kevin Nolan in the rational design of inhibitors for the two catalytic sites of the enzyme prostaglandin endoperoxide synthase. In Dublin, I learnt the practicalities of molecular modelling and computational chemistry and was awarded a research grant from the Health Research Board.
Always fascinated by biology, I then moved to Strasbourg to work in the group of Prof. Dino Moras at the Structural Biology and Genomics Department of the Institute of Genetics and Molecular and Cellular Biology (IGBMC). Dino and co-workers are trying to understand, by making use of an ensemble of biochemical and biophysical techniques, how nuclear receptors regulate genetic transcription. I was in charge of the modelling. Some results will soon be published.
In October 2008 I joined the Department of Pharmaceutical and Medicinal Chemistry at Saarland University, Saarbruecken, where I developed models for different enzymes, namely HSD2, CYP11B1, CYP11B2 and RDH1, as well as a new method for protein multiple sequence alignment with restraints derived from flexible structural alignment (MUSA-REFLEXSA).
May 2010. I was appointed at the Luxembourg Centre for Systems Biomedicine (LCSB, University of Luxembourg).
The company ProSciens, Computing & Molecular Sciences will be registered in Luxembourg in January 2011. Exciting times ahead.